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For example, a vertical line arising from 10% change in BMI in Trial 1 intersects the IMCIVREE and placebo curves at approximately 61%, and 5%, respectively, which correspond to the values shown in Table 1

The key factor is the total cumulative time the vial has spent out of the fridge

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Clinical trials showed no cancer signal with tirzepatide compared to control groups , though it's important to recognize these studies were not designed or powered to detect rare malignancies or those with long latency periods

The $249 monthly cost reflects this legitimate manufacturing pathway while delivering substantial savings compared to brand alternatives

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