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If the treatment causes a detrimental shift in microbial composition, leading to adverse effects like gastrointestinal distress or immune suppression, healthcare providers could intervene by adjusting the treatment regimen or introducing probiotic interventions to restore microbial balance

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iners fluctuates considerably during the early stages of pregnancy, with a notable increase observed as vaginal cleanliness declines (84)

Nevertheless, many of the large-scale cardiovascular trials have reported the effects of DPP-4 inhibitors on aspects of diabetic nephropathy, specifically changes in urinary protein excretion, in glomerular function over time, and in the risk of progression to end-stage renal disease [47, 48, 84]

Gene-specific actions of transcriptional coregulators facilitate physiological plasticity: evidence for a physiological coregulator code