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SGLT-2 inhibitors cause robust reduction of HHF and the renal outcome, and moderate reduction of CV or total deaths and MACE [13]

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In a randomized, double-blind, placebo-controlled study over 6 months in overweight but otherwise healthy adults, supplementation with Moro blood orange extract was associated with significantly greater improvements in body mass, BMI, waist circumference, hip circumference, and fat distribution (including both visceral and subcutaneous fat) compared to placebo

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