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After four years, the increase in plaque volume was significantly greater in women taking the placebo (+53.1%) than in women taking the garlic supplement (-4.6%), while no significant difference in plaque volume was found between garlic (+1.1%) and placebo (+5.5%) in men (94, 95)

Furthermore, PPI network among hub targets, composed of 14 nodes and 78 edges, was also constructed (Fig

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Bone age assessment may be considered if growth concerns arise