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T cells from mice immunized to TPO react strongly to TPO sequence 540-559, and when immunized with this peptide, develop hypothyroidism and thyroiditis

However, individual responses can vary, and not everyone may experience significant increases in appetite

Journal of Ethnopharmacology, 151 (1), 528-535

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Theres also an option for a nuclear medicine test that directly measures the GFR, but this test is inconvenient and costly compared to commonly used formulas, such as the Cockcroft-Gault or the Modification of Diet in Renal Disease formulas