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It reflects a broader hypothesis that coordinated signaling across three metabolic receptors may produce effects that differ from those achieved through GLP-1 alone or through combined GLP-1 and GIP agonism

The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development

Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice

2010) and the management priority shifts to careful metabolic monitoring and prenatal care

doi: 10.1039/b111229e