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For TH1-related cytokines, we also found a significant interactions between diet and treatment (diet and treatment interaction: F (1,54) = 8.136, R 2 = 0.102, p = 0.003) and the main effect of sex was also significant (main effect of sex: F (1,54) = 9.488, R 2 = 0.119, p = 0.001)