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Such effects are observed in diseases such as warm autoimmune hemolytic anemia [132, 133], pemphigus vulgaris [134,135,136], and generalized MG (gMG) [137,138,139]

For example, certain foods, such as fermented foods, vinegars, cured meats, citrus fruits, and bananas, can be high in histamine or contain histamine-releasing compounds

Luo J, Chen J, Deng ZL, Luo X, Song WX, Sharff KA, Tang N, Haydon RC, Luu HH, He TC

Since B vitamins are water-soluble, its unlikely that you will consume too much of these nutrients through food or by taking a B-complex supplement as directed

Both above studies suggest that MTHFR polymorphisms might enhance the environmental risks (low folate intake, traumatic stress at childhood) for MDD via the interaction between genetic and environmental factors

While this may sound impressive, none of these assertions are based on human trials