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Although the structure of the CBSCH004 complex has not yet been reported, Q222A mutation largely abolishes the inhibitory activity of CH004, suggesting that Gln222 is a key residue for its binding

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Different bariatric surgical techniquesincluding biliopancreatic diversion, gastric bypass and mini-gastric bypass, recommended when class 3 obesity cannot benefit from diet and exercise alonecan induce dissimilar effects on antioxidant balance [59,60,61]

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