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Furthermore, opposite to what we had anticipated, chronic semaglutide treatment enhanced the conditioned reinforcing properties of a food-associated cue as well as progressive ratio responding for a small food reward

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For health care providers, several points are important: Oral GLP-1-based therapies may increase acceptability for patients who are reluctant to use injectable medications

Beyond simple appetite suppression, semaglutide addresses the biological mechanisms that drive hunger and metabolic regulation