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Multiple cellular processes are considered to contribute to this functional decline and these are collectively referred to as the hallmarks of aging and these include processes like genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis 1

Data collection We recorded the data of all patients followed for CVS in our center (n=26)

A systematic review and meta-analysis of clinical trials on the effects of glutamine supplementation on gut permeability in adults

Saunders, Elliott-Sale, et al., 2017)

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