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It has also been known for 80+ years that carnosine is a key intra-cellular buffer due to its nitrogen containing imidazole side ring, which can accept (buffer) H + (Bate-Smith, 1938), and slow the decline in muscle pH during intense exercise (Baguet, Koppo, Pottier, & Derave, 2010)

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This is a clinically meaningful improvement and stands in stark opposition to the results for primary insomnia

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Measuring LPL activity in PHP is needed to determine whether a patient or sample has compromised LPL function leading to HTG and its co-morbidities