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Often, the best results come from combining medication with lifestyle adjustments such as diet, exercise, and stress management

This is particularly relevant for patients experiencing significant weight reduction

Variants in GLP1R, GIPR, FTO, and MC4R genes may help provide context for how your body processes these medications and should be interpreted with a qualified healthcare provider

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Use of WEGOVY for this indication is supported by a 68-week, double-blind, placebo-controlled clinical trial in 201 pediatric patients aged 12 years and older with a BMI corresponding to 95th percentile for age and sex and from studies in adult patients with obesity [see Clinical Studies (14.3)]

35,36 The dual GLP-1/GIP RA tirzepatide is the first pharmacotherapy to be approved for the treatment of moderate-to-severe obstructive sleep apnea in adults with obesity