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Fishers exact test was performed for PTEN enrichment in GBM samples ranked according to PSPH expression levels

Retrieved 16 November 2009

However, there is still a long journey from this first-in-class compound to a safe and effective drug

No Phase 3 human trials have been completed

10.1038/oby.2002.126 145 HannaertP.Alvarez-GuerraM.PirotD.NazaretC.GarayR

Metabolic stability studies indicated valproates metabolism is not primarily eliminated through CYP450, suggesting that the in vivo interaction likely results from inhibition of -oxidation or glucuronidation