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Val3-Asp4 interact with similar residues at the base of the binding cavity to those observed for residues 2 and 3 of the other peptides, however, with the exception of Y148 1.43 , these were very transient (Supplementary Table 3)
By designing nanomaterials responsive to these enzymes, it is possible to achieve selective activation and targeted antimicrobial delivery
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Not because it is the leading cause of acute liver failure in the United States (which should be enough of a reason), but because half of the overdoses are unintentional, indicating a general lack of awareness of the toxic potential of acetaminophen (which can be fatal)
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