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Deng et al., 2020

1 In a study of 3,297 patients with established cardiovascular disease already on standard treatment, the addition of semaglutide reduced the composite outcome of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke by 2.3 percentage points as compared with placebo (6.6% vs

Side Effects, Safety, and Long-Term Tolerability Contrave's most common side effects include nausea, constipation, and insomnia (attributable to bupropion stimulation)

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Risks of Taking Weight Loss Medicines Without Medical Supervision Social media often presents these medicines as miracle injections, but they are still prescription medications

The 12 mg group achieved 24.2% weight loss at 48 weeks in Phase 2, and 28.7% at 68 weeks in the Phase 3 TRIUMPH-4 trial