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doi: 10.1016/j.mce.2011.08.008 8 HaradaNHanadaKMinamiYKitakazeTOgataYTokumotoHet al

The copper coordination is essential for the compounds biological functions, including stimulation of collagen synthesis, promotion of angiogenesis, and modulation of inflammatory responses

According to Jia et al

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The other is the use of an acid-resistant capsule designed to withstand the stomach's corrosive fluids long enough to preserve the contents for the intestines

Some researchers find that abdominal injections produce fewer reactions than thigh injections, though this varies individually