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These were, i.e., in the cerebellum (ibuprofen [107], paracetamol [61]), the cerebral cortex (diclofenac [106,108], celecoxib [105]), the frontoparietal cortex (concussive brain trauma) [78], the hippocampus and the cerebral cortex (insulin) [62], and the parietal neocortex and hippocampus (cuprizone [80]) (note, cuprizone application [80] was an extremely high regimen highly over those commonly applied to mimic multiple sclerosis in rats [268,269])

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Angiogenesis occurs with contribution from VEGF and its receptors, eNOS and EGR-1, all of which have been shown to be affected and upregulated by BPC-157 [8, 38, 39, 7072]

Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine [13-15]