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Overall, the PubMed search showed that the use of the glutathione transporter as a target for developing brain-targeting agents was a relatively new and less explored field
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Some describe modest renewed weekly losses for 48 weeks after cagrilintide reaches maintenance
Research has demonstrated the antioxidant action of S -acetyl-glutathione rivals that of vitamins C and E
Furthermore, SAE remains notably underdiagnosed and undertreated, and survivors often develop persistent long-term neurocognitive sequelae, including hippocampus-dependent memory impairment, psychiatric disorders and functional disability, which severely impact quality of life ( Oxidative stress is central to SAE pathogenesis, driven by an imbalance between excessive reactive oxygen species (ROS) production and impaired antioxidant defense systems (Yan et al., 2022)
