No pills
People who were overweight or obese lost significant weight while taking retatrutide, which enabled them to be more active and reduced knee pain by an average of 4.5 points or about 76% based on pain scores from whats known as the Western Ontario and McMaster Universities Osteoarthritis Index
As of mid-2026, retatrutide has not been approved by the MHRA in the UK or the FDA in the United States
High-fat foods should be limited on tirzepatide as they compound the medication's gastric emptying delay, commonly causing prolonged nausea, bloating, and discomfort
Monitor yourself closely for severe nausea, vomiting, or abdominal pain, and focus on staying hydrated with small sips of water or electrolytes
"We know there are some patients who just won't take an injectable medication." The starting dose of the Wegovy pill will cost $149 for patients paying out of pocket, under an agreement announced in November with the Trump administration