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J Alzheimers Dis 19(4):12051219 Kim S, Moon M, Park S (2009 Sep 1) Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinsons disease

There is currently no established evidence in UK regulatory documents that semaglutide alters thermoregulation , and reports of cold sensitivity are largely anecdotal

In addition to ASO drugs, siRNA therapies offer unique solutions for CVDs

Interestingly, 5-HT 2C receptor modulators, and in particular 5-HT 2C agonists, have been identified as potential antipsychotic medications with fewer side effects (for review, see Rosenzweig-Lipson et al., 2012)

This makes Semaglutide, in the form of Wegovy, generally more effective for weight loss than Ozempic, though both provide meaningful results

I am Michael Calore, WIRED's director of Consumer Tech and Culture