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Common GLP-1 injection include Exenatide, the first approved GLP-1 receptor agonist that requires twice daily or once weekly injections (long-acting formulation) Liraglutide, It is injected once a day to treat type 2 diabetes and obesity

Pivotal trials: what the NEJM data show Semaglutide STEP-1 (2021) and SELECT (2023) STEP-1 (Wilding et al., NEJM 2021) randomized 1,961 adults over 68 weeks on semaglutide 2.4 mg/week

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