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83 Autotaxin inhibits autophagy via the AMPK pathway, thereby disrupting the mucosal barrier and aggravating intestinal inflammation, and AMPK agonists can significantly ameliorate this process, preventing intestinal inflammation and maintaining the integrity of the mucosal barrier

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Non-neuronal sources of tachykinins in the airways were reported in epithelium (SP) [109] and airway smooth muscle [110]

This observation aligns with the results of the MTT assay, suggesting that our treatment does not directly kill inflammatory cells but rather modulates their state to rescue cell damage