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Clinical studies have shown that patients can expect significant weight loss (around 5-10% of their body weight) after about 6 months of consistent use, although individual results may vary based on lifestyle factors such as diet and exercise

Tirzepatide was a 39-amino acid linear synthetic peptide that shared19 amino acids with human GIP, conjugated to a C20 fatty diacid moiety via a linker connected to the lysine residue at position 20

NAE reports associated with GLP-1 RAs were extracted, and disproportionality analysis was performed to identify NAEs significantly disproportionately related to these agents, which were defined as GLP-1 RA-related NAEs in this work

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