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This metabolic acceleration can temporarily elevate oxidative stressthe imbalance between free radicals and antioxidant defensesparticularly during the first 48 weeks of therapy initiation

Gut-directed therapies targeting intestinal inflammation and bacterial translocation are also under investigation

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These drugs are increasingly recognized not only for their therapeutic benefits but also for their potential to prevent serious chronic conditions

The metabolic support process develops progressively over weeks to months, with optimal results requiring consistent administration alongside proper nutrition and exercise

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