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They outlined a minimum dataset that should be collected: Before treatment begins At the end of dose titration Every three months for at least one year Analyzing this information over time will help build a clearer picture of how GLP-1s affect people with PWS, including both potential benefits and side effects

Sustained intakes below ~1,200 kcal/day in women and ~1,5001,800 kcal/day in men jeopardize not only muscle mass, but also endocrine, neurologic, and micronutrient homeostasis

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In contrast, it is difficult to completely prevent the development of cardiovascular events and CKD by hypoglycaemic therapy alone

The goal is always the lowest effective dose that delivers meaningful outcomes