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After 56 weeks: Placebo group lost 1.2% of body weight Recommended dose (7.5/46 mg) group lost 7.8% of body weight Top dose (15/92 mg) group lost 9.8% of body weight The EQUIP trial enrolled 1,267 adults with class II and III obesity (BMI 35+)

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Stopping Criteria require all of the following : [1] Acetaminophen level is 25-50% from peak value

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