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Glutathione in the prevention of cisplatin induced toxicities
For example, in Hordeum vulgare leaves challenged with the powdery mildew fungus, Blumeria graminis , the fungal infection led to a significant decrease in APX and GR activity in whole-leaf extracts of resistant variety but caused no significant change in the susceptible one
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Supportively, upon platinum resistance, high-grade serous ovarian cancer cell lines OVCAR4 and OVCAR5 exhibit higher intracellular cholesterol contents than the corresponding parental cell lines [117]
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