Reports suggest that phosphorylation of Ras-related protein (Rab10), an endocytic sorting protein by LRRK2 is crucial for glucose transporters type 4 (GLUT4) translocation to the neuronal plasma membrane
Other factors such as LRPPRC (Leucine-rich pentatricopeptide repeat-containing protein), Hsp90 (Heat shock protein 90), and Hsp60 (Heat shock protein 60) are involved in mitochondrial function and maintenance, where their levels decrease in PD (Han et al
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Pharmacol Rep (2016) 68(2):44350
The amino 1mq compound has unique properties in the lab that makes it useful for researchers studying metabolic processes