glp 1 neurotransmitter GLP-1 and the Degenerating Brain: Exploring Mechanistic Insights and Therapeutic Potential Targeting GLP-1, GIP & GCG

In basic terms, GLP-1 drugs make you feel full for a longer amount of time so you dont consume as many calories during the day

2 , pky073 (2018)

Nat Rev Endocrinol 2020;16(11):615616

Diabetes Care 44(3):765773 Kim WJ, Lee SJ, Lee E, Lee EY, Han K (2022) Risk of incident dementia according to glycemic status and comorbidities of hyperglycemia: a nationwide population-based cohort study

Fifty-eight patients with ST-segment-elevation MI and thrombolysis were randomized to receive either saline (n = 40) or exenatide (n = 18, 10 g SC and 10 g as an IV bolus 5 min before the onset of reperfusion plus 10 g SC twice daily on the following 2 days) to evaluate whether this GLP-1R agonist could reduce the area of necrosis

Nausea is the most common side effect of both semaglutide and tirzepatide, particularly during dose escalation phases