10.1104/pp.104.046441 Plant Physiol
Altogether, these findings argue for an active role of TAM in promoting tumor angiogenesis through VEGF- and MMP-9-dependent pathways
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Past research has highlighted the medicinal properties of durian fruit pulp extract, including its antiproliferative effects on various human cancer cell lines 30,31,32,33,34 , neuroprotective effect on the human neuroblastoma cell line SH-SY5Y 35 , and antidiabetic effect on the HepG2 cell line by regulating glycolysis regulatory genes 32
This hydrophobic appendage promotes non-covalent, high-affinity binding to circulating albumin, effectively turning the plasma protein into a reversible depot and raising the terminal half-life to roughly one week, compatible with once-weekly (OW) dosing in humans, which enhances accessibility compared to daily regimens [38]
