Mitochondrial fission is the process of mitochondrial splitting, but excessive mitochondrial fission can lead to mitochondrial dysfunction, oxidative stress, and fragmentation of the mitochondrial network [26]
Support with diet: Increase your intake of garlic, onions, and broccoli
The results may be slower, but they are more sustainable and biologically restorative
In addition, SFN treatment ameliorated colon and caecal mucosal epithelial damage in mice with N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced bladder cancer through up-regulation of tight junction protein expression, downregulation of IL-6 release, and prevention of gut dysbiosis (He et al., 2018)
Collectively, the role of ferroptosis in OA is multifaceted and has been extensively explored in recent studies
Furthermore, a sulforaphane intervention study in a cohort of healthy participants augmented peripheral and brain glutathione (Sedlak et al., 2017), an antioxidant readily implicated in various neurological functions (Dwivedi et al., 2020)