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G., Skeen, J

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Critically, UGT inhibition (not substrate activity) correlates with hepatotoxic potential.A drugs inhibition of UGT enzymes is a direct indicator of increased hepatotoxicity risk

Moreover, sustained elevation of CORT can induce the upregulation of pro-inflammatory cytokines (e.g., IL-1, IL-6, and TNF-), enhance microglial activation, disrupt bloodbrain barrier (BBB) integrity, and facilitate the infiltration of peripheral immune cells into the central nervous system (CNS), thereby exacerbating neuroinflammation (Hooper et al., 2018)

The main factors influencing photocatalytic properties of TiO 2 are particle size, crystal composition, band gap, and surface hydroxyl density