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Glutathione (GSH), the most abundant antioxidant in the lens, decreases progressively with age, especially in the lens nucleus

Add the fact that both NAD+ and glutathione drop sharply with age, and it is easy to feel pressure to pick the right one

Rather than focusing on short-term anecdotes, serious investigators try to map which pathways appear most responsive, what concentrations are relevant in their models, and how repeatable those findings are in different systems

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