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In those with persistent disease, TSH suppression should be maintained below 0.1 mU/l indefinitely in the absence of specific contraindications

A common complaint is the early adjustment to digestive issues

Sakhaee K, Maalouf NM, Sinnott B

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It is worth noting, however, that the authors reported that pioglitazone was superior to SUs in providing cardiovascular protection to those who were either free from evident cardiovascular disease or were in the early stages of diabetes [52]

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