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These findings also confirm the chronicity of obesity and suggest ongoing treatment is required to maintain improvements in weight and health." A new European consortium known as Sophia (Stratification of Obese Phenotypes to Optimize Future Obesity Therapy), led by scientists at University College Dublin, is now attempting to investigate this in more detail

One conceived in the wake of recombinant DNA technology in the 70s, shaped by early anglerfish experiments in the 80s, and given further structure by elegant biochemical studies of GPCR signaling in the 90s

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It provides the most effective symptomatic treatment for PD and can be used either as monotherapy or in combination with other agents

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