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However, The function of mTOR in controlling Treg cells is still up for debate, though

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Ferriani RA, Silva de S MF

Despite major advances in the field concerning the neurobiological substrates underlying the ES-induced increased risks for adverse neurobehavioral outcomes and psychopathology, the underlying mechanisms remain complex, multi-faceted, not yet completely understood and often hard to target, rendering the development of effective interventions challenging [8, 9]

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In total, 98.0% of the patients completed the trial and the vital status was known at the end of the trial for 99.6%