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The PBMC and PMNs layers were carefully recovered in 800 l volumes, mixed with 800 l PBS, centrifuged, and removed the excess solution, leaving the pellet in 25 l volume

The accumulation of amyloid- (A) is a pathological hallmark of AD, with A being produced through the cleavage of amyloid precursor protein (APP) by -and -secretases, generating peptides of A of varying length (Murphy and LeVine, 2010)

CAS 946870-92-4