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brief room-temperature exposure during transport is acceptable Handling Use aseptic technique when reconstituting and aliquoting Avoid repeated freeze-thaw cycles to preserve peptide integrity Follow all institutional biosafety guidelines

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This has been clearly demonstrated by elegant crystallography studies of a recombinant soluble form of rat FcRn in a complex with a mouse IgG2a Fc fragment [24], then of human FcRn alone [23, 24], and also of human FcRn in complex with both ligands [26]