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"Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people"

According to the Cleveland Clinic, B12 deficiency can cause very tired or weak feelings, plus neurological, psychological and physical symptoms (Narayana Health, n.d.)

Initial energy improvements are often felt within the first one to two weeks

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A deficiency can occur for several reasons, such as pernicious anemia (a condition where the body cannot absorb vitamin B12 from the diet), certain medical conditions (e.g., Crohn's disease, celiac disease), surgical removal of part of the stomach or intestine, or strict vegetarian/vegan diets if not adequately supplemented