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Retatrutide also improved multiple cardiometabolic parameters, including blood pressure, lipids, waist circumference, and liver fat (82% reduction in hepatic steatosis)

They discovered that the interaction between endogenous GLP-1 and its receptors in the NST, but not AP, is vital for weight loss

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Top-selling drug charts in 2025H1 show GLP-1 agonists displacing traditional blockbusters, reflecting how obesity and diabetes treatments have become huge revenue drivers

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