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Depending on the chemotherapy regimen, severe CIPN (i.e., symptoms that limit self-care activities of daily life or are life threatening), classified as grade 3 or 4, can occur in up to 35% of patients and symptoms can be so bothersome that they force dose-modifications or treatment discontinuation (Lustberg 2024
Centrum Silver was the multivitamin used in the trial
GHK-Cu occupies a different category
Annals of Neurology, 36(3), 356-361
The accelerated turnover has cleared years of accumulated congestion
In particular, this is due to the wide range of physiological roles that GH has, making it an important player in many biological conditions and diseases
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