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According to a meta-analysis evaluating 453 trials and 21 antidiabetic treatments, oral semaglutide reduces all-cause mortality and cardiovascular death, with the lowest odds ratios (ORs) among the treatments evaluated (empagliflozin, liraglutide, extended-release exenatide, dapagliflozin, dulaglutide, lixisenatide, canagliflozin, pioglitazone, DPP-4 inhibitors, subcutaneous semaglutide, sulphonylureas) [56]

Palmitoylethanolamide (PEA) 500 mg

doi: 10.11622/smedj.2018043 133 CohenSJanicki-DevertsDMillerGE

doi:10.1017/s0029665123002689

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