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We also summarize newly proposed mechanisms associated with hepatoprotection and tumor suppression, such as attenuation of hepatocellular stress through inhibition of the NEDD9/FAK/AKT cascade and a potential role in cell-cycle regulation via the HDAC/p21 axisalthough the latter remains to be validated in MASLD-specific models

For instance, compounds like kojic acid show promising inhibitory effects but face limitations due to cytotoxicity or allergic reactions

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In other words, evidence from a few studies suggests that GLP-1-agonist-induced weight loss may lead to expected levels of muscle loss while improving muscle quality, but further research is needed

If this helped you feel a little less lost around food, Im really glad

A mindful and responsible eating approach can enhance the benefits of GLP-1s, especially when managing GLP-1 food noise