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Considering the latter possibility, treatments that were considered failures in previous clinical trials could be reanalyzed for potential efficacy in ALS, taking into account the duration of the disease at the start of therapy. Therefore, using diagnostic criteria that enables earlier identification of the disease and a change in the physicians attitude towards offering an early diagnosis and treatment could result in better ALS patient outcomes.

Int J Epidemiol 54(2):dyaf026 Lau C-HE et al (2018) Determinants of the urinary and serum metabolome in children from six European populations

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