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Another study developed pH/ROS dual-responsive metformin-released-enhanced self-healing bifunctional polyethylene glycol-co-poly(glycerol sebacic acid)/dihydrocaffeic acid and L-arginine co-grafted chitosan hydrogel to enhance wound healing through decreased inflammation and enhanced angiogenesis in a rat type II diabetic model

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Once the weekly milligram target is set, reconstitution determines only the concentration and syringe draw not the dose itself