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Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress

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Exact dosing varies by experimental design and species but generally follows preclinical trial standards for NNMT inhibitors

The primary completion date is February 2027

MOTS-c is a short peptide (16 amino acids), which makes it relatively resistant to the enzymatic degradation that degrades larger peptides, but also means that reconstitution technique and storage conditions matter considerably