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Among the GLP1-RA agents, once-weekly semaglutide may be especially promising in type 1 diabetes, as this agent has demonstrated superiority over other GLP1-RAs in terms of glycaemic control and weight loss in type 2 diabetes, as well as good tolerability [56]

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There are many methods that have been used for stress reduction, such as supplementation with the hormone DHEA and maintaining sex hormone balance