The honest summary is that BPC-157 appears to be a pleiotropic signaling molecule
PMC 12313605
Hence, targeting oxidative stress in IBD diagnosis emerges as a promising avenue with far-reaching implications
If we treat 14 mg oral as roughly comparable to 0.5 mg weekly injectable Ozempic for orientation, then an older patient on oral tablets loses about 3.7 kg over the 30-ish weeks (bear in mind, evoke trials are 2 years long), and if around 45 percent of that loss is lean mass (or thereabouts) that is about 1.7 kg of muscle gone
So is it fixing something that in some people, for whatever reason we don't understand, that signaling is not working the way it's supposed to
Elsevier, pp 6669 Oyama J, Maeda T, Kouzuma K, Ochiai R, Tokimitsu I, Higuchi Y, Sugano M, Makino N (2010) Green tea catechins improve human forearm endothelial dysfunction and have antiatherosclerotic effects in smokers