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FDA press announcement (2025) 11

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For instance, a study on ME/CFS demonstrated the efficacy of the tricarboxylic acid (TCA) cycle metabolite oxaloacetate in improving symptoms (Cash and Kaufman, 2023), patients showed marked improvements in fatigue scores as measured by the Chalder Fatigue Questionnaire in a randomized, double-blind, placebo-controlled trial using AXA1125

Hingson, R

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According to the Diabetes UK , an estimated 6.3 million people are at an increased risk of type 2 diabetes in the UK based on blood sugar levels